Resveratrol and Myo-inositol for PCOS

PCOS ladies listen up! A new study has shown that a combination of resveratrol and myoinositol are more effective than metformin plus pioglitazone in improving menstrual regularity, hirsutism (abnormal hair growth) and regulating hormone levels in obese women with PCOS. 

 

The details: 

  • Hassan et al. (2023) compared a combination of two natural ingredients resveratrol and myoinositol with two medications commonly prescribed for PCOS, metformin and pioglitazone (these are antidiabetic medications which work on the insulin driven aspect of PCOS).

  • In this 12 week double-blind, randomised control trial, 110 obese women aged 20 to 35 with PCOS and  irregular anovulatory cycles were split into two groups - the medication group and the nutraceutical group. 

  • In comparison to the medication group, the combination of resveratrol and myoinositol significantly reduced:

    •  Weight, BMI, waist-hip ratio, and blood pressure 

    • Serum testosterone levels and abnormal hair growth/hirsutism

    • LH, FSH and ovarian volume (which are often abnormally elevated/skewed in women with PCOS)


The real kicker? After 12 weeks of intervention, 84.1% of women taking resveratrol plus myoinositol had regular menstrual cycles, compared to only 18.2% of participants taking metformin and pioglitazone having menstrual regularity.

Have you tried resveratrol and myoinositol for your PCOS? It is important to check with a qualified practitioner (like me!) to see if these products are appropriate for you. As always reach out if you need help regulating your hormones.  


PMID: 36169918  DOI: 10.1007/s12020-022-03198-2

Hayley Brass